Quinine

Name: Quinine
SKU: 0

CAS No.:130-95-0
Molecular Formula：C20H24N2O2
Molecular Weight: 324.42

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product description

Quinine(130-95-0), an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine. Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.

Chemical Properties

Property	Value
Melting point	173-175 °C(lit.)
Alpha	-172 º (c=1, EtOH)
Boiling point	462.75°C (rough estimate)
Density	1.1294 (rough estimate)
Bulk density	110-140kg/m3
Vapor pressure	0Pa at 25℃
Refractive index	1.6250 (estimate)
Fp	>110°C (>230°F)
Storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Solubility	H2O: soluble
Form	Crystalline Powder
Pka	8.52(at 25℃)
Color	White
PH Range	Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)
PH	9.0 (0.5g/l, H2O, 20℃)
Odor Type	Odorless
Optical Rotation	[α]25/D 165°, c = 2 in ethanol
Water Solubility	slightly soluble
Sensitive	Light Sensitive
Hydrolytic Sensitivity	2: reacts with aqueous acid
Merck	14,8061
BRN	91867
Major Application	Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system
LogP	3.17 at 25℃
CAS DataBase Reference	130-95-0(CAS DataBase Reference)
NIST Chemistry Reference	Quinine(130-95-0)
EPA Substance Registry System	Quinine (130-95-0)

Safety Information

Property	Value
Hazard symbols	Xn, Xi
Hazard class codes	36/37/38-42/43-22-20/22-20/21/22-36/38
Safety descriptions	22-26-36/37-45-37/39-36-7
UN dangerous goods number	1544
WGK Germany	3
RTECS number	VA6020000
F	8
TSCA	TSCA listed
Hazard class	6.1(b)
Packing group	(not specified)
HS code	29392110
Storage class	11 - Combustible solids
Hazard class (category)	Acute toxicity, Category 4, Oral Skin sensitization, Category 1
Hazardous substances data	130-95-0 (Hazardous Substances Data)
Antimalarial use	Still used primarily for treatment of plasmodium resistant to synthetic antimalarials. Also used as antipyretic for colds, influenza, and cramp; quinine may have toxic effects on the eye, apparently due to an immune reaction, and may also affect male reproductive capacity.
Toxicity	(See antimalarial use description above)

Product Usage

Quinine, a natural alkaloid historically derived from cinchona bark, is a multifunctional compound with significant applications in medicine and the food industry. Its most critical role remains in the pharmaceutical sector, where it is a vital anti-malarial medication used to treat severe Plasmodium falciparum infections and as an ingredient in treatments for nocturnal leg cramps. In the food and beverage industry, Quinine is the signature bittering agent in tonic water and various bitter lemons, providing the quintessential flavor profile for classic cocktails. Beyond consumption, it is utilized in analytical chemistry as a standard fluorescence reference due to its highly predictable quantum yield under UV light. Additionally, its unique chemical properties allow it to serve as a chiral resolving agent in asymmetric organic synthesis, assisting in the production of pure enantiomers for advanced drug manufacturing.

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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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